A Functional Medicine Approach To Treating Crohn’s Disease

Crohn’s disease is a chronic inflammatory condition that can cause intense abdominal pain, fatigue, and a whole host of uncomfortable gut symptoms. It can severely impact a person’s quality of life, especially if you’ve been unable to get flare-ups under control.
While conventional medicine generally focuses on symptom control through medications and, if the disease progresses, surgery, functional medicine offers a more holistic approach.
By addressing the root causes of symptoms through gut health, diet, and lifestyle changes, you can see an improvement in your condition and a more sustainable path to managing Crohn’s long-term.
Functional Over Conventional
Functional medicine emphasizes the root causes of a condition and bio-individuality over symptom management. When it comes to managing Crohn’s, a combination of lifestyle, diet, and functional therapies can improve overall gut health and restore balance.
Conventional treatments generally focus on addressing flare-ups through anti-inflammatory drugs, immunosuppressants, or even surgery, despite the fact Crohn’s is a recurring condition.
While there’s certainly a time and place for medication and conventional therapies, Crohn’s is a multifaceted disease influenced by environmental factors, diet, and microbiome imbalances. A reactive approach to flare-ups doesn't account for these factors, and isn't doing anything to address the root cause of the problem.
Doctors who fail to take a holistic wellness approach to Crohn’s disease also aren’t recognizing that every person reacts to interventions differently. This can set patients up for more side effects and flare-ups.
Helping a patient feel better in the short term without a plan for long-term gut health isn’t a sound approach, either. Functional medicine practitioners emphasize the idea that there is no one solution to how you go about healing your gut.
By focusing on the whole person and promoting self-awareness and personal agency around health, functional medicine empowers patients to manage Crohn’s in a sustainable way and improve their digestive health and quality of life.
In-Depth Lab Testing
Crohn's is typically diagnosed using a combination of blood tests, stool tests, and imaging studies (there is no single test to diagnose Crohn’s).
Blood work may be used to check inflammatory markers, autoantibodies, nutritional deficiencies, and kidney and liver function. You may also need a comprehensive stool analysis to evaluate digestive function and rule out infection.
From there, your doctor may order X-rays, CT scans, MRIs, and/or procedures like a colonoscopy or endoscopy to get a bigger picture of the condition’s effects on your intestinal and colon health.
But while this kind of testing is necessary for diagnosis, in functional medicine, we also want to go deeper to get an understanding of the "why" behind your condition. It's not that we want to overload you with tests, but we do want to make sure we're using the tools available to us get to the root cause of your symptoms.
The goal is to individualize treatment based on those results and rule out other underlying issues that may be exacerbating your condition, such as gut dysbiosis or nutrient deficiencies.
I’ve watched patients experience dramatic changes to their overall health by addressing leaky gut or malabsorption issues that conventional testing missed. In functional medicine, testing isn’t just a diagnostic tool but a way to uncover the root causes of your condition.
Crohn’s Diet Plan
The Standard American Diet (SAD) is full of potential triggers for Crohn’s and intestinal inflammation. If you’ve been diagnosed with Crohn’s disease, you may have already noticed that certain foods trigger your symptoms while other foods don’t.
While every person’s trigger foods are slightly different, almost all Crohn’s patients benefit from reducing their intake of the following foods:
- Lectin-containing foods like beans and legumes
- Nuts and seeds
- Gluten-containing grains
- Processed foods (e.g. microwave popcorn and processed meats like bacon)
- Raw vegetables
- Caffeine
- Sorbitol, xylitol, or other sugar alcohols
- Alcohol
- Soda
- Spicy foods
- Raw fruits
I recommend reducing these foods as much as possible, especially in the first few months, while you also work on improving your gut health. Keep an eye on your symptoms. Once symptoms improve, you may be able to be reintroduce certain foods and be more flexible with your Crohn’s diet and your dietary patterns.
An elimination diet can help you get to the bottom of your food triggers and intolerances. In this diet, you remove several potentially triggering foods from your diet, then reintroduce them one by one to monitor your reactions. A food diary can help you keep track.
Some people with Crohn’s also have lactose intolerance, for example. (1) While a serving of probiotic-rich yogurt can be great for settling inflammation in the gut for some people, it won’t do you any good if you’re sensitive to dairy.
For any gut health concerns, following an anti-inflammatory diet is always recommended. This way of eating emphasizes whole, unprocessed foods that are rich in nutrients like omega-3 fatty acids, antioxidants, and probiotics, which promote gut health and support a balanced gut microbiome.
There are lots of delicious foods that can benefit your gut health and reduce inflammation when you’re managing Crohn’s:
- Lean proteins
- Fatty fish
- Cooked, non-cruciferous vegetables (e.g. potatoes and asparagus)
- Low-fiber fruits (e.g. bananas, peaches, honeydew melon)
- Eggs
- Fermented foods
If you’re experiencing a flareup, be gentle with your diet. Choose foods that are easy to digest, even bland, like white or brown rice, cooked greens, and rice noodles. As a general rule, people with Crohn’s benefit from cooked foods like soups, stews, and stir-fried dishes.
If you have Crohn’s disease, you should work closely with your healthcare provider or dietitian and follow their instructions on diet. That said, if they’re not open to dietary or lifestyle changes to help you manage your condition, that’s a huge red flag and a sign to find a new doctor.
Chronic inflammation can mess with your gut, weaken your immune system, and affect your mental health. Get instant, 24/7 access to expert advice with my self-guided course: Mastering Autoimmune Conditions & Inflammation With Functional Medicine.
Functional Therapies
Functional therapies for Crohn’s focus on natural, holistic approaches to reducing inflammation while managing symptoms. These alternative therapies work alongside diet and address lifestyle factors that contribute not only to symptoms but also to immune function.
Here are two that I’ve seen success with in my patients battling gut conditions:
- Acupuncture: Clinical trials show promising results that acupuncture could be helpful for Crohn’s. (2) The idea is that the anti-inflammatory practice positively affects an imbalance in gut microbiota and intestinal barrier function.
- Cannabis: A good number of people with Crohn’s are already using cannabis to deal with symptoms, and studies support possible therapeutic benefits. (3) If cannabis is legal in your state, you may want to try experimenting with different doses and ratios.
Supplements
Certain supplements can help to improve gut health, reduce inflammation, and calm an overactive immune system. Here are a few of my favorites:
- Fish oil: Omega-3 fatty acids found in fatty fish and fish oil supplements may reduce underlying inflammation present in Crohn’s. Studies suggest they may keep patients in remission longer, but more research is needed to understand exactly how this works. (4)
- Probiotics: Probiotics including strains of Lactobacillus and Bifidobacterium help balance gut bacteria and reduce inflammation. (5) Fermented foods like sauerkraut and tempeh are also good sources of probiotics if you tolerate them well. You can try my probiotic supplement here.
- Prebiotics: Prebiotics are fibers that feed healthy gut bacteria, supporting a balanced microbiome and better digestive health. You can take prebiotic supplements and/or take in prebiotics through food. Bananas, artichokes, and avocado are good food sources, but as with probiotics, you’ll want to make sure you tolerate them.
- Saffron: This spice has antioxidant and anti-inflammatory effects that may reduce gastrointestinal tract inflammation. Studies show it may also neutralize free radicals that damage sensitive intestinal tissues in cases of intestinal bowel disease (IBD). (6)
- Curcumin: Derived from turmeric, curcumin is a powerful anti-inflammatory that can reduce gut inflammation. Studies show it also has antimicrobial properties for a healthier gut microbiome. (7)
- Boswellia serrata: Boswellia is often recommended to reduce inflammation in gut health conditions and osteoarthritis. (8) Some people do report stomach pain at the start of taking this one, so make sure to keep track of your symptoms as you add new therapies.
- Slippery elm: Slippery elm is a known demulcent that reduces irritation and inflammation in the gut. It’s also a natural prebiotic. I believe in it so much that I incorporate it in my Gut Feelings supplement duo for improved digestive and mental health.
It’s also crucial that you address any vitamin or mineral deficiencies that may be making your symptoms worse, especially if you have persistent intestinal permeability issues.
It's common to see deficiencies in vitamin D, calcium, vitamin B12, iron, and zinc in patients with Crohn’s. Healthy levels of each are essential for immune function and combating Crohn’s symptoms.
Lifestyle Changes
Diet is an essential piece, but a few additional lifestyle changes are also linked to a reduction of flare-ups and improved gut health overall. Let’s start with one that doesn’t just cause gut dysfunction but harms your immune system and hormonal health: stress.
Chronic stress and excess cortisol production can trigger flare-ups and worsen symptoms. (9) If you don't already have set coping strategies, I recommend yoga, meditation, or gratitude practices for stress management. Adequate sleep and a solid bedtime routine also coincide with managing stress.
If you’re a smoker with Crohn’s, take steps to quit today. Smoking worsens inflammation and can trigger not only flare-ups but progression of the disease. (10)
Finally, regular exercise is good for digestive health and combating inflammation. If you’re not feeling your best, be gentle with yourself. I’ve seen success in patients who have adopted yoga for Crohn’s as a way to reduce stress and get some movement into their daily routine.
Getting To The Root Cause Of Crohn’s
Crohn’s disease can be overwhelming, painful, and uncomfortable, but here’s what I tell my patients: You can dramatically improve autoimmune symptoms with individualized treatment. Completely reversing Crohn's disease may not always be possible, but functional medicine interventions can do way more than just reduce flare-ups.
If you’re ready to tackle Crohn's disease and improve your gut health with a tailored approach, book a consultation. As one of the first functional medicine telehealth clinics in the world, we provide webcam health consultations for people around the globe.
FAQs
Crohn’s disease is a type of IBD that causes inflammation in the digestive tract, often affecting the small intestine and colon. Unlike ulcerative colitis, an IBD that affects the colon, Crohn’s can impact any part of the GI tract.
There is no single cause of Crohn’s, but age, genetics, smoking, and chronic stress are all risk factors for developing the disease
Crohn’s disease symptoms are linked to your body’s immune system response to unregulated inflammation. They include:
- Diarrhea
- Bloating
- Abdominal pain
- Rectal bleeding and pain
- Unintended weight loss
- Loss of appetite
- Nutrient deficiencies
- Fatigue
- Low mood or depression
- Brittle nails
- Hair loss
- Nausea and vomiting
These symptoms must be chronic and moderate to severe to be diagnosed with Crohn's disease. As disease activity progresses, patients with Crohn’s may experience worsening inflammation along the small and large intestines.
IBD is different from irritable bowel syndrome (IBS) in that it is characterized as an autoimmune disease.
That means the underlying cause of Crohn’s is an immune response malfunction that causes the immune system to attack the body’s own tissues. In the case of Crohn’s, the body attacks the intestinal lining, leading to localized inflammation.
IBS is a functional disorder affecting how the gut works, but without causing inflammation or damage.
Although the causes of Crohn’s disease and ulcerative colitis aren’t fully understood, there is a known link between food, intestinal microbes, and the health of the gut microbiome.
We know a high intake of processed foods, sugars, and unhealthy fats promotes harmful bacteria, while a diet rich in fiber, fruits, and vegetables supports beneficial bacteria. (11) A healthy balance of gut bacteria means lower inflammation and, potentially, a lower risk of IBD flares.
Crohn’s disease isn’t a fatal condition, and people who manage the condition can live healthier, fuller lives. Left unmanaged or mismanaged, Crohn’s can increase your risk of severe complications like infection, malnutrition, bowel obstructions, fistulas, and colon cancer.
Studies show that the cancer risk, in particular, is linked to chronic inflammation over time that speeds up abnormal cell growth. (12)
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FUNCTIONAL MEDICINE CONSULTATIONS FOR PEOPLE AROUND THE WORLD
- Asfari, M.M., Sarmini, M.T., Kendrick, K., et al. (2020). Association between inflammatory bowel disease and lactose intolerance: fact or fiction. The Korean Journal of Gastroenterology, 76(4), 185-190.
- Song, G., Fiocchi, C., & Achkar, J.P. (2019). Acupuncture in inflammatory bowel disease. Inflammatory Bowel Disease, 25(7), 1129-1139.
- Naftali, T. (2020). An overview of cannabis based treatment in Crohn's disease. Expert Review of Gastroenterology and Hepatology, 14(4), 253-257.
- Farrukh, A. & Mayberry, J.F. (2014). Is there a role for fish oil in inflammatory bowel disease? World Journal of Clinical Cases, 2(7), 250-252.
- Wang, X., Zhang, P. & Zhang, X. (2021). Probiotics regulate gut microbiota: an effective method to improve immunity. Molecules, 26(19), 6076.
- Rashid, M., Rashid, R., Saroya, S., et al. (2024). Saffron as a promising therapy for inflammatory bowel disease. Nutrients, 16(14), 2353.
- Burge, K., Gunasekaran, A., Eckert, J., et al. (2019). Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection. International Journal of Molecular Sciences, 20(8), 1912.
- Catanzaro, D., Rancan, S., Orso, G., et al. (2015). Boswellia serrata preserves intestinal epithelial barrier from oxidative and inflammatory damage. PLoS One, 10(5), e0125375.
- de Dios-Duarte, M.J., Arias, A., Durantez-Fernández, C., et al. (2022). Flare-ups in crohn's disease: influence of stress and the external locus of control. International Journal of Environmental Research and Public Health, 19(20), 13131.
- Nicolaides, S., Vasudevan, A., Long, T., et al. (2020). The impact of tobacco smoking on treatment choice and efficacy in inflammatory bowel disease. Intestinal Research, 19(2), 158-170.
- Stidham, R.W. & Higgins, P.D.R. (2018). Colorectal cancer in inflammatory bowel disease. Clinics in Colon and Rectal Surgery, 31(3), 168-178.
- Asakura, H., Suzuki, K., Kitahora, T., et al. (2008). Is there a link between food and intestinal microbes and the occurrence of Crohn's disease and ulcerative colitis? Journal of Gastroenterology and Hepatology, 23(12), 1794-1801.
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BY DR. WILL COLE
Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, Gut Feelings, and The Inflammation Spectrum.

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