Exposed To Mold? Exactly How To Get Mold Toxicity Testing To Find Out For Sure

Exposed-To-Mold--Exactly-How-To-Get-Mold-Toxicity-Testing-To-Find-Out-For-Sure

As a functional medicine practitioner, I see countless people dealing with the damaging effects of mold exposure on a daily basis. From respiratory issues to brain problems and other chronic illnesses, mold is one of the most insidious, undetected threats to our health we face currently. And although there are no official statistics regarding the prevalence of mold, it is estimated that up to 47% of homes (1) have some sort of mold-related damage.

That’s why it is imperative for us to understand not just the signs and symptoms of mold exposure but how to test for mold exposure to know for sure. So if you believe mold is behind your symptoms, read on to learn exactly how to test for mold exposure in your home and how to get tested for mold toxicity.

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Signs and symptoms of mold exposure

Mold toxicity is an insidious problem that doesn’t always have a clear set of symptoms. Mold can quietly infiltrate your living spaces, triggering a range of health concerns that you might not recognize until years later. In fact, researchers are beginning to connect the dots between mold exposure and a variety of chronic health problems, coining the term Chronic Inflammatory Response Syndrome - or CIRS for short - to encompass any sort of health problem related to mold exposure.

But with that said, there are some common symptoms that often go along with immediate mold exposure that you should be aware of. If you experience any of these symptoms, you may be living in a moldy environment.

  • Respiratory problems: Persistent coughing, wheezing, shortness of breath, or sinus congestion can all be red flags, as mold spores often irritate the respiratory system.
  • Allergies: Mold is a potent allergen, causing symptoms like sneezing, runny or itchy nose, itchy or watery eyes, and even worsening asthma. Mold exposure can also exacerbate seasonal allergies.
  • Skin Problems: Rashes, hives, and unexplained skin irritations may also indicate mold exposure.
  • General Discomfort: Chronic fatigue, headaches, or unexplained discomfort should not be dismissed, as these symptoms are often attributed to mold.

Mold exposure, if left unchecked, can lead to more severe health issues over time. Again, researchers are looking deeper at the impact of mold toxicity on multiple modern-day health problems with surprising findings. On some level, mold has been implicated in a slew of long-term health problems, including: 

Therefore, if you are experiencing any of these signs, it's vital to consider testing your environment for mold as a proactive measure as well as running labs on yourself to determine if you have any mold toxicity problems. To learn more about the top signs of mold exposure, check out my article here.

Assessing your environment

If you suspect mold exposure is a factor in your health case, one of the first steps in restoring your health is to assess your home or work for the presence of mold. You may be surprised at just how stealth mold can be, creeping up in areas of your home that you would least expect (even your car)!

One way to assess your environment is through at-home mold testing kits. Not only are they easy to use, they can be a more cost-effective option compared to professional evaluations. Most at-home mold testing kits typically include collection swabs, petri dishes, or air sampling cassettes, along with detailed instructions on how to collect samples from various areas in your work or home. These samples are then sent off to a laboratory for analysis or can be analyzed by you following the kits instructions.  

While at-home kits can be a good choice, the effectiveness of these kits largely depends on the quality of the kit and how well you adhere to the instructions. Although they can provide a general overview of mold presence, they may not always yield definitive results, as mold species and concentration levels can be complex to interpret without professional expertise. Plus, factors like environmental conditions and mold spore activity can vary, at-home kits not as reliable. 

Ultimately, testing kits can serve as a useful initial step in identifying potential mold problems, but for a more thorough evaluation and precise remediation, consulting with a certified mold inspector or environmental specialist is often recommended.

How to test for mold exposure

Just like there is no one set of symptoms that indicate mold toxicity, there is also not one single test that determines if you’ve been exposed to mold. Since mold toxicity is such a complex health problem, there are many things going on beneath the surface that can indicate mold exposure depending on the specific type of mold in your environment and your particular biochemistry. Therefore, there are multiple tests that your doctor may recommend for the most accurate assessment of your health.

1. Mycotoxin labs

This is one of the first places I like to start when it comes to testing for mold exposure. These labs look for the presence of mycotoxins in your urine and antibody production against mycotoxins in your blood. They can also look for the presence of other biotoxins that are released from bacteria or viruses that can mimic mold toxicity.

2. C4a

C4a, or complement component 4a, is a protein in the immune system that plays a crucial role in regulating inflammation and immune response. When you’re exposed to mold, your immune system goes into overdrive, leading to an increased production of C4a as it attempts to combat the perceived threat from mold spores and mycotoxins. High levels are one of the most common indicators of mold exposure and can lead to tissue damage and chronic inflammation.

3. Transforming Growth Factor Beta1

While important to the health of your cells, when high, this cytokine can have (8) pro-inflammatory effects and indicate a potential mold exposure.

4. MMP-9

This enzyme works to stimulate the immune response but when high can contribute to out-of-control inflammation and is correlated with mold exposure.

5. ACTH/Cortisol

Adrenocorticotropic hormone (ACTH) controls the release of your body's stress hormone, cortisol, which can be high in cases of mold exposure.

6. SOCS3

This acronym stands for "suppressor of cytokine signaling 3," which can be elevated directly from mold exposure or from other imbalances caused by mold, leading (9) to a variety of symptoms.

7. MSH

This hormone acts as an anti-fungal and antimicrobial so when it’s low, mold toxicity is likely a factor.

8. Genetic testing

Your doctor may also want to run genetic testing as certain genetic variants within the HLA and MTHFR gene (10) families may influence your risk of developing mold toxicity.

Next Steps

Working with a functional medicine practitioner is one of the best ways to overcome mold toxicity. Not only will they be able to run the labs necessary to look at the above biomarkers, they will know how to interpret the results and translate them into actionable steps to reclaim your health.

In my telehealth functional medicine clinic, we specialize in comprehensive health care. By looking at your environment, lab work, genetics, and current lifestyle, we are able to put together a plan of action that tackles the underlying factors contributing to mold toxicity symptoms from every angle.

For further reading on mold, check out my articles on the top foods most likely to contain mold, exactly where mold can be hiding in your home, and what you can do to overcome mold toxicity issues.

As one of the first functional medicine telehealth clinics in the world, we provide webcam health consultations for people around the globe. 

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References:

  1. Citation: Park, J.-H.; Cox-Ganser, J.M. NIOSH Dampness and Mold Assessment Tool (DMAT): Documentation and Data Analysis of Dampness and Mold-Related Damage in Buildings and Its Application. Buildings 2022, 12, 1075. https://doi.org/10.3390/ buildings12081075
  2. Vasefi, Maryam et al. “Environmental toxins and Alzheimer's disease progression.” Neurochemistry international vol. 141 (2020): 104852. doi:10.1016/j.neuint.2020.104852
  3. Ekwomadu, Theodora et al. “Mycotoxin-Linked Mutations and Cancer Risk: A Global Health Issue.” International journal of environmental research and public health vol. 19,13 7754. 24 Jun. 2022, doi:10.3390/ijerph19137754
  4. Empting, L D. “Neurologic and neuropsychiatric syndrome features of mold and mycotoxin exposure.” Toxicology and industrial health vol. 25,9-10 (2009): 577-81. doi:10.1177/0748233709348393
  5. Islam, M.T., Mishra, S.K., Tripathi, S., de Alencar, M.V.O.B., e Sousa, J.M.d.C., Rolim, H.M.L., de Medeiros, M.d.G.F., Ferreira, P.M.P., Rouf, R., Uddin, S.J., Mubarak, M.S. and Melo-Cavalcante, A.A.d.C. (2018), Mycotoxin-assisted mitochondrial dysfunction and cytotoxicity: Unexploited tools against proliferative disorders. IUBMB Life, 70: 1084-1092. https://doi.org/10.1002/iub.1932
  6. Benito-León, Julián, and Martin Laurence. “The Role of Fungi in the Etiology of Multiple Sclerosis.” Frontiers in neurology vol. 8 535. 16 Oct. 2017, doi:10.3389/fneur.2017.00535
  7. Yang, Zhenggang et al. “Regulation of insulin and leptin signaling by muscle suppressor of cytokine signaling 3 (SOCS3).” PloS one vol. 7,10 (2012): e47493. doi:10.1371/journal.pone.0047493
  8. Clark, D A, and R Coker. “Transforming growth factor-beta (TGF-beta).” The international journal of biochemistry & cell biology vol. 30,3 (1998): 293-8. doi:10.1016/s1357-2725(97)00128-3
  9. Carow, Berit, and Martin E Rottenberg. “SOCS3, a Major Regulator of Infection and Inflammation.” Frontiers in immunology vol. 5 58. 19 Feb. 2014, doi:10.3389/fimmu.2014.00058
  10. Valtonen, Ville. “Clinical Diagnosis of the Dampness and Mold Hypersensitivity Syndrome: Review of the Literature and Suggested Diagnostic Criteria.” Frontiers in immunology vol. 8 951. 10 Aug. 2017, doi:10.3389/fimmu.2017.00951

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BY DR. WILL COLE

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Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, Gut Feelings, and The Inflammation Spectrum.

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