Can Saffron Help With ADHD Symptoms?

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Living with ADHD can be challenging, and treating it is a complicated equation of balancing trade offs. Impacting focus, attention, and overall quality of life, ADHD requires focused interventions that vary from person to person, often including pharmaceutical treatment.

Currently, there is great interest in exploring alternative treatments beyond conventional medications which are known to cause significant side effects. One intriguing option gaining attention, especially in the functional medicine world, is saffron. Saffron, sometimes referred to as “red gold,” or the most expensive spice in the world offers delightful culinary benefits as well as numerous health benefits including anti-inflammatory agents, antioxidants, and very possibly--promising therapeutic results in people with ADHD.

Scientific Evidence Supporting The Use Of Saffron For ADHD

Recent studies have shown promising results linking saffron to improvements in ADHD symptoms. Its active compounds, such as safranal and crocin, exhibit neuroprotective and antioxidant properties, which may enhance neurotransmitter function and regulate mood and cognition.

A recent literature review exploring saffron’s therapeutic effects (1) mentioned a study in which teachers monitored students using saffron in addition to traditional ADHD meds, and those students had over a 50% reduction in symptoms as reported by their teachers.

Another review (2) looked at a pilot study comparing saffron against traditional ADHD medication and found saffron to be a promising treatment in isolation, especially against hyperactivity.

While the current scientific evidence leaves room and recommends further study, these initial findings are quite promising for the future of saffron as an effective and safe ADHD treatment.

Is Saffron A Realistic ADHD Medication Alternative?

In short--maybe. But the evidence is not strong enough yet to truly consider it an alternative. Instead, consider it a compliment to doctor-recommended medications and therapies.

While saffron shows promise, it’s important to approach it as a complementary rather than a replacement therapy for ADHD medications. Its efficacy can vary from person to person, and more research is needed to establish its role in mainstream treatment protocols.

How Does It Compare To ADHD Medications?

When comparing saffron (Crocus sativus) to traditional ADHD medications like methylphenidate, the evidence suggests differing approaches to symptom management. Methylphenidate, a commonly prescribed stimulant, acts quickly to enhance dopamine and norepinephrine levels, effectively improving focus and attention in many individuals with ADHD.

In contrast, saffron’s mechanism involves modulating neurotransmitter systems and reducing oxidative stress, potentially offering a gentler, natural alternative. Clinical studies indicate that saffron may effectively alleviate ADHD symptoms, albeit with a slower onset and potentially fewer side effects, especially on sleep. The importance of this should not be underestimated because healthy sleep patterns are paramount to overall health, especially for anyone struggling to manage symptoms like those associated with ADHD. Further research is needed to fully establish saffron’s efficacy and safety compared to traditional medications like methylphenidate.

In terms of efficacy, conventional treatments often provide quicker and more pronounced symptom management. Safety-wise, however, saffron generally poses far fewer risks than prescription medications, which can carry potential severe side effects like insomnia, appetite suppression, and mood swings.

Recommended Dosage

For those considering saffron, typical dosages range from 30 mg to 100 mg daily, standardized to contain 1.5% crocin. Always consult with a healthcare provider to determine the right dosage based on individual health needs.

And make sure the supplements you consider are well-researched and vetted by experts. Quality is of utmost importance when using herbs and spices for their medicinal benefit.

Taking Saffron With ADHD Medication

Combining saffron with ADHD medications should be approached under medical supervision. Potential interactions could affect efficacy or safety, so it’s important to discuss this with your healthcare provider.

Potential Risks

While generally safe, saffron can cause mild side effects such as dizziness or nausea in some individuals. High doses may lead to more severe reactions, so you should start with a low dose and monitor for any adverse effects.

Who Shouldn't Take Saffron?

For some, saffron may not be the best suited alternative. You should not take saffron if you are:

  • pregnant or breastfeeding
  • allergic to saffron
  • allergic to plants in the Iridaceae family (which includes crocus and iris)
  • undergoing surgery in the next several weeks
  • Struggling with certain medical conditions, such as bipolar disorder, schizophrenia, or hormone-sensitive conditions like breast cancer or endometriosis

Don’t Walk This Journey Alone

Navigating ADHD can be confusing and frustrating. Incorporating alternative treatments can be overwhelming, but in the end could be life-changing and incredibly effective. But weighing your options and finding the right treatment for your unique needs requires focused expert attention.

To consult with a functional medicine expert with specialty in these types of complementary and alternative treatments, schedule a telehealth consult today.

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  1. Omidkhoda, S. F., & Hosseinzadeh, H. (2022). Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence. Iranian Journal of Basic Medical Sciences, 25(8), 913.
  2. Golden, G. S. (1974). Gilles de la Tourette's syndrome following methylphenidate administration. Developmental Medicine & Child Neurology, 16(1), 76-78.

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

Our content may include products that have been independently chosen and recommended by Dr. Will Cole and our editors. If you purchase something mentioned in this article, we may earn a small commission.

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BY DR. WILL COLE

Evidence-based reviewed article

Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, Gut Feelings, and The Inflammation Spectrum.

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