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Functional Medicine

Trauma, Toxins & Spiritual Curses: The Truth About “Mystery Illnesses” | Dr. Jessica Peatross

Published June 12, 2025  •  3 minutes read
Avatar Of Dr. Will ColeWritten By: Evidence-Based Reviewed Article

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What if the root cause of your symptoms isn’t in your head – but hiding in your environment, your mouth, or even your past trauma? In this episode, I sit down with Dr. Jessica Peatross, a brilliant integrative medicine physician who left conventional medicine after seeing firsthand how often patients were dismissed, misdiagnosed, and left without answers. Together, we explore what’s really behind “mystery illnesses” – from mold, parasites, and stealth infections to unresolved trauma and toxic dental work. We also talk about why drainage is the missing piece in most detox protocols, how to know if a parasite cleanse is right for you, and why emotional healing has to be part of any long-term wellness plan. Dr. Peatross is one of the most thoughtful voices in root-cause medicine, and I’m so excited to share this conversation with you.

Dr. Jessica Peatross is a distinguished medical doctor specializing in integrative medicine and  health. With a passionate commitment to patient-centered care and a holistic approach to healing, Dr. Peatross has established herself as a leading advocate for comprehensive wellness practices. Dr. Peatross earned her medical degree from the University of Louisville and completed her residency training in Internal medicine. Her journey into integrative medicine began early in her career, driven by a desire to explore alternative modalities that complement traditional medical practices. This led her to pursue additional training in functional medicine, nutritional therapy, ozone, Gerson therapy, biological medicine, and mind-body medicine, enriching her ability to offer personalized treatment plans that address the root causes of illness. She transitioned from a 7-year tenure as a board-certified hospitalist to specialize in functional medicine, focusing on Lyme disease, mold, and environmental toxicities. She founded Aegis Formulas, a root cause supplement company, and Wellness Plus, a holistic health practice dedicated to integrative wellness. Recently launching a successful virtual clinic, Dr. Peatross is dedicated to solving medical mysteries and empowering patients through comprehensive, personalized care.

A few of my favorite things we cover in this episode: 

  •  Why mold, Lyme, parasites, and heavy metals are often the true root cause of chronic illness
  • How trauma and unresolved emotional wounds can weaken the immune system
  • The connection between dental infections and systemic health issues
  • Why chronic symptoms often get dismissed as anxiety or depression in conventional medicine
  • Dr. Peatross’ personal story of leaving traditional medicine after seeing how often patients were gaslit or misdiagnosed
  • The biggest mistakes people make when detoxing (and how to do it right)
  • The truth about parasite cleanses – what works, what’s hype, and who really needs one
  • The foundational steps everyone should take to support drainage and mitochondrial health
  • Her approach to testing and personalized protocols for tough cases
  • Why she believes we are living in a “parasite renaissance”

Links to things we talked about in this episode: 

  • Right now LMNT is offering a free 8-count Sample Pack of their most popular drink mix flavors with any purchase. This is a great way to find your favorite LMNT flavor, or share with a friend. Get yours at DrinkLMNT.com/artoeingwell.
  • If you’re ready to truly nourish your skin and body from within, Pique is offering 20% off plus a FREE rechargeable frother and glass beaker with my exclusive link: Piquelife.com/WillCole.
  • Head to MANUKORA.com/WILLCOLE to save up to 31% plus $25 worth of free gifts with the Starter Kit.
  • Listeners can get my exclusive 25% discount off their first order at cowboycolostrum.com using code WILLCOLE, and trust me, your taste buds and microbiome will be thanking you.
  • Take proactive care of your health and head to OPositiv.com/WILLCOLE or enter WILLCOLE at checkout for 25% off your first purchase.

Happy listening and we hope you learned a little bit more on the art of being well!

If you like what you hear, please rate and review the podcast, hit subscribe and pass it along to a friend.

In Health,

Dr. Will Cole

Supplement Guide

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Dr. Will Cole

Dr. Will Cole, IFMCP, DC, leading functional medicine expert, consults people around the world via webcam and locally in Pittsburgh. He received his doctorate from Southern California University of Health Sciences and post doctorate education and training in functional medicine and clinical nutrition. He specializes in clinically researching underlying factors of chronic disease and customizing a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. Dr. Cole was named one of the top 50 functional medicine and integrative doctors in the nation and is the best selling author of Ketotarian and The Inflammation Spectrum.

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