The Serotonin-Depression Myth, Antidepressant-Placebo Controversy + A Functional Approach To Mental Health

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Welcome to another episode of the "Mental Health Is Physical Health" series. Join me and my dedicated functional medicine telehealth team as we navigate the intricate landscape of mental well-being. In this enlightening conversation, we explore the historical context of mental health, unravel controversies surrounding antidepressants, and shed light on the vital importance of informed consent in medication decisions. Discover the profound impact of inflammation on mood and brain function, and gain valuable insights into supplements, therapies, and mindfulness practices that can assist on your journey to better mental health. If you're ready to reclaim control over your mental health, this episode is your starting point. Take the first step today towards a healthier, happier you. Plus, listen until the end for an intimate conversation from a previous patient.

Studies Referenced:

  1. Review: benefits of antidepressants over placebo limited except in very severe depression. BMJ Mental Health: https://mentalhealth.bmj.com/content/13/2/49
  2. Placebo Effect in the Treatment of Depression and Anxiety. Frontiers in Psychiatryhttps://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2019.00407/full
  3. The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular Psychiatry :https://www.nature.com/articles/s41380-022-01661-0
  4. Cold plunge article for benefits , code drwillcole for discount: https://drwillcole.com/functional-medicine/is-cold-therapy-worth-it-a-functional-medicine-guide-to-cold-plunges-cryotherapy-more
  5. Sunlighten article, Save up to $600 on your purchase by mentioning Dr. Will Cole. Click the link in bio : https://drwillcole.com/detoxing-toxins/the-top-8-infrared-sauna-health-benefits-how-to-find-the-best-sauna-for-you


A few of my favorite things we cover in this episode:

  • Overview of mental health history, addressing stigma.
  • Explore controversies surrounding antidepressants and relevant data.
  • Importance of informed consent in medication usage.
  • Delve into serotonin's role and the associated antidepressant research.
  • Introduction to the functional medicine perspective on mental health.
  • Discuss how inflammation influences mood and brain function.
  • Highlight supplements, therapies, and tools for mood enhancement.
  • Insight into mindfulness practices to overcome mental health challenges.


Links to things we talked about in this episode:

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  • Right now, when you go to justthrivehealth.com and use promo code: DRWILL you can get 20% off a 90 day bottle of JustThrive Probiotic and Just Calm...That’s like getting a month for FREE!
  • LMNT came up with a fantastic offer for us. Just go to DrinkLMNT.com/WILLCOLE to get a free sample pack with any purchase!
  • Elevate your hair wellness routine this year with Vegamour. For a limited time get twenty percent off your first subscription order by going to VEGAMOUR.com/willcole and use code willcole at checkout.

Happy listening and we hope you learned a little bit more about the art of being well!

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In health,

Dr. Will Cole

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The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

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BY DR. WILL COLE

Evidence-based reviewed podcast

Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is the host of the popular The Art Of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, The Inflammation Spectrum and the brand new book Gut Feelings: Healing the Shame-Fueled Relationship Between What You Eat and How You Feel.