Air Hunger, FDA Thyroid Controversy, Peptides, PCOS & Mold | Ask Me Anything

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In this AMA episode, I tackle some of the most layered and emotional health questions we’ve received yet. I share what really causes air hunger and why mold, Lyme, and trauma can keep your nervous system in fight-or-flight. I also break down the FDA’s recent attempt to ban natural thyroid medications, what it means for millions of patients, and why functional medicine voices are fighting back. We dive into PCOS in teenagers - a topic close to my heart as both a clinician and parent - and the root causes that conventional medicine often ignores. Finally, I weigh in on new peptides like retatrutide, the hype around weight loss medications, and how to use them responsibly while still addressing the true drivers of metabolic dysfunction.
Please take action: Sign the petition to stop the FDA from banning natural thyroid medications. Patients deserve choice in their care, and this move could limit access for years.
Sign here: https://chng.it/5y486fKmPr
A few of my favorite things we cover in this episode:
- Air hunger (shortness of breath) - causes like mold, Babesia, Lyme, viruses, and nervous system dysregulation, plus treatment approaches (breathwork, vagal nerve stimulation, HBOT, nutrients, peptides).
- FDA controversy over banning natural desiccated thyroid (NDT) medications - Synthroid vs NDT, clinical trials, functional medicine advocacy, and patient choice.
- PCOS in teenagers - conventional gaps, root causes (insulin resistance, toxins, genetics, stress), diet strategies (cyclical keto, nutrient density), supplements (inositol, omega-3s, vitamin D, berberine), and family/environmental connections.
- New peptide therapies - retatrutide and GLP-1 agonists, benefits for weight loss, insulin resistance, fatty liver, cardiovascular risk, plus cautions about root cause resolution and side effects.
- The importance of bio-individuality, environment, stress, and monitoring labs in functional medicine.
Links to things we talked about in this episode:
- Go to Quince.com/willcole for free shipping on your order and three hundred and sixty-five-day returns.
- Sign up for your one-dollar-per-month trial and start selling today at SHOPIFY.COM/willcole.
- Go to shopremi.com/WILLCOLE and use code WILLCOLE at checkout for 50% off.
- You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/WILLCOLE and using code WILLCOLE at checkout.
- Use my link to give the new AG1 flavors a try, plus a FREE Welcome Kit: drinkag1.com/willcole.
Happy listening and we hope you learned a little bit more on the art of being well!
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In Health,
Dr. Will Cole
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BY DR. WILL COLE
Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, Gut Feelings, and The Inflammation Spectrum.