Perimenopause, Gut Secrets & The Longevity Laser That Hollywood Is Obsessed With | Lucy Goff

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I've been a quiet fan of LYMA for a while. Every time I go to see Joanna Czech in New York, it's part of the session. And when Lucy Goff walked into my studio in Pittsburgh — having flown from London to New York and then hopped a very small, very bumpy plane to get here — I wanted to understand the full picture behind what she's built.

The origin story alone is worth the listen. Lucy collapsed at eight months pregnant in a hospital lobby in London. She'd been sitting in a hairdresser's chair across the street from The Portland Hospital and felt something go terribly wrong. She walked herself across the road and woke up on an operating table with severe preeclampsia, a baby in the NICU, and what turned out to be septicemia — a blood infection that couldn't find an antibiotic match for six weeks. She spent six weeks in intensive care. When she came out, her body was finished. She went to Harley Street doctors who told her to give it time. The supplement industry didn't serve her either — she was taking things, but they were generic, under-dosed, and not bioavailable in any meaningful way. The pharmaceutical world had nothing for her. And then, almost by accident, her mother took her to a clinic in Geneva where a man named Professor Paul Clayton happened to be at a conference. He wasn't even part of the clinic. He sent her a package a few weeks later. Within two weeks of taking it, she felt herself again.

What followed was LYMA — a supplement brand built on the principle that patented, peer-reviewed ingredients, dosed at effective levels and delivered through high-tech systems that survive the stomach, are a completely different category from what's on the average shelf. We go deep on the ingredients: HydroCurc (the only form of turmeric where less than 10% of the delivery system is the carrier), Affron (a patented saffron that's been proven as effective as fluoxetine in published data, with zero side effects, and works within one hour), and ID Squared — their gut powder that uses prebiotic fibers in every length to act in every part of the gut, not just the sections that standard inulin can reach. Lucy had colitis for years. She couldn't button her jeans by 3pm. Six months on ID Squared, that's gone.

And then there's the laser. The LYMA laser is the one thing I keep having to explain to people who see it in my skincare routine. It looks like a red light device. It is not. Lucy breaks down the exact difference — why LED is a scattered light that can only act in the epidermis (the top layer, the one that's about to fall off), and why a cold laser that is monochromatic, coherent, and polarized can penetrate nine centimeters into the body, reach the dermis, and biologically switch gene expression. Including the SIRT1 longevity gene, which was expressed six times in the dermis using the LYMA laser in a study published in Aesthetic Surgery Journal — and not at all using an LED equivalent built by Imperial College London. You can't get that result by damaging skin. You can't get that result from a panel or a mask. And you get to do it in your house, every day, for 15 minutes.

Use code WILL10 for 10% off the LYMA Laser. Offer not valid on LYMA Laser PRO: https://lyma.sjv.io/drwillcole

A few of my favorite things we cover in this episode: 

• Septicemia at 8 months pregnant: collapsing in a hospital lobby, six weeks in ICU, medical gaslighting ("don't be dramatic"), and the chance encounter with Professor Paul Clayton at a clinic in Geneva that changed everything
• Why the supplement industry failed Lucy: generic, under-dosed, and not bioavailable — and why patented peer-reviewed ingredients at effective doses are a different category entirely
• HydroCurc: how less than 10% of the carrier system means more actual curcuminoids reach the body — vs. liposomal turmeric where 90% is carrier
• Affron (patented saffron): as effective as fluoxetine and citalopram in published data, zero side effects, works within one hour — vs. six weeks for antidepressants
• Why 95% of LYMA customers are perimenopausal women — and why HRT is amazing but not the full picture
• The sleep-inflammation-serotonin cycle: how fragile sleep transitions get hijacked by high inflammation and low serotonin
• The Victorian paradox: eating 4,500 calories/day of unprocessed food with 20g prebiotic fiber — the least degenerative disease era in modern history
• ID Squared gut powder: different-length prebiotic fibers that act in every part of the gut — not just the parts that inulin and FOS can reach
• Lucy's colitis history: too restricted to button her jeans at 3pm — resolved in six months on ID Squared
• The LYMA laser: why it isn't LED, why LED can't change the dermis, and why being monochromatic + coherent + polarized is the difference
• 9 centimeters of biological penetration: through skin, muscle, and ligament — down to the bone
• SIRT1 longevity gene expressed 6x in the dermis with the LYMA laser vs. not at all with LED equivalent — published in Aesthetic Surgery Journal
• Zero damage: unlike ablative lasers that damage to stimulate collagen, this switches the gene expression without inflammation
• 78% wound size reduction in diabetic ulcer clinical trial — placebo group got worse
• Martha Stewart uses two lasers while hanging upside down. Courteney Cox uses two. Joanna Czech ignored Lucy, then became the first US professional adopter after a summer in the Hamptons with no pigmentation
• Protocol: 3 minutes per section, 15 minutes total, every day

Episode Sponsors:

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Happy listening, and we hope you learned a little bit more on the art of being well!

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In Health,

Dr. Will Cole