Ozone Therapy Myth Busting: Everything You Need To Know For Long COVID, Lyme, Mold, Cancer, Gut Health & More | Micah Lowe

WATCH THE FULL-LENGTH EPISODE HERE ON YOUTUBE! 

Ozone is one of the therapies I’ve seen make a meaningful difference for people who feel stuck, especially when we’re dealing with complex inflammation and biotoxin-related issues like mold, chronic Lyme, long COVID, and autoimmune patterns. But it’s also one of the most misunderstood tools in the integrative space. That’s why I wanted this episode to be a true resource, breaking down what ozone is, where it came from, and how it’s actually used clinically.

Micah Lowe joins me for a full ozone deep dive, starting with the basics: ozone is O3, and that extra oxygen atom is what gives it its unique effects. We talk about the most common misconceptions, including why ozone is not something you want to inhale, and why delivery method and dosing are everything. When used appropriately, it’s a therapy that can support the body in powerful ways without needing hype or exaggerated claims.

Micah also lays out a clear framework for understanding what ozone is doing in the body: immune modulation, supporting antioxidant response, improving microcirculation, and enhancing oxygen efficiency. From there, we cover the practical application. We discuss IV ozone, rectal insufflation as a common at-home option, topical ozonated oils, and why ozone has become a standout tool in oral health and dentistry.

If you’ve been curious about ozone but overwhelmed by the noise online, this conversation will help you understand the “why” and the “how” so you can make informed decisions with the right medical guidance.

A few of my favorite things we cover in this episode: 

• Why ozone is one of the biggest “needle movers” for complex inflammatory and biotoxin cases (mold, chronic Lyme, long COVID, IBD)
• The origin story and history of ozone therapy (early Germany, WWI wound care, modern research landscape)
• What ozone actually is (O3) and why that “extra” oxygen atom matters
• The biggest safety misconception: ozone is not meant to be inhaled, and dosing and delivery are everything
• The core “why it works” framework: immune modulation, antioxidant response, microcirculation support, oxygen efficiency
• Ozone delivery methods explained: IV ozone, rectal insufflation (at-home option), ozonated oils, ear insufflation, and more
• Dentistry and skin benefits: why ozonated oil is a staple for oral health and topical healing
• Why ozone isn’t “FDA mainstream” and what that says about incentives, bureaucracy, and access to low-cost therapies
• Advanced ozone: IBU (extracorporeal blood oxygenation and ozonation) and why it requires an experienced physician

Products Mentioned:  

• Simply O3

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Happy listening and we hope you learned a little bit more on the art of being well!

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In Health,

Dr. Will Cole