Dr. Anurag Singh: How To Enhance Mitochondrial Health, Postbiotics & The Latest Longevity Research

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In this episode of The Art of Being Well, I sit down with Dr. Anurag Singh, a leading expert in mitochondrial health and the Chief Medical Officer at Timeline. We dive into the critical "Hallmarks of Aging" study and the science behind mitochondrial dysfunction, macroautophagy, and chronic inflammation. Are environmental toxins accelerating aging? Dr. Singh shares strategies to address declining mitochondrial health, from dietary interventions to the role of postbiotics like Urolithin A. Whether you're interested in muscle health or longevity, this episode provides practical advice for protecting your cellular health.

Anurag Singh is the Chief Medical Officer at Timeline that develops next generation advanced nutritional and skincare products targeting improvements in mitochondrial and cellular health. With a M.D. in internal medicine and a Ph.D. in immunology, Dr Singh's work bridges the gap between cutting-edge researchers who develop of novel solutions and medical clinicians who address the practical concerns of patients.  He is a global leader in the study of mitochondrial function with experience that includes work at top consumer health (Nestlé, Nestlé Health Science) and startups companies (Amazentis/Timeline). Dr Singh has authored > 40 articles for top science journals, been awarded >15 patents and has designed and led > 50 randomized clinical trials. His research over the past decade across multiple clinical trials on the postbiotic Urolithin A and its health benefits has led to the launch of multiple consumer products.

A few of my favorite things we cover in this episode: 

  • The significance of the "Hallmarks of Aging" study and its importance.
  • Mitochondrial dysfunction, impaired macroautophagy, and chronic inflammation.
  • Factors contributing to accelerated aging or mitochondrial dysfunction today.
  • The impact of environmental toxins on mitochondrial health.
  • Strategies to address declining mitochondrial health.
  • An overview of Urolithin A and its benefits for muscle health.
  • The role of diet in triggering longevity pathways, particularly focusing on plant compounds like postbiotics created by the microbiome.
  • The potential benefits of Urolithin A for individuals taking GLP-1 agonists, particularly in preventing muscle loss.

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Happy listening and we hope you learned a little bit more on the art of being well!

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Dr. Will Cole

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BY DR. WILL COLE

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Dr. Will Cole, DNM, IFMCP, DC is a leading functional medicine expert who consults people around the globe, starting one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole provides a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, Gut Feelings, and The Inflammation Spectrum.